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Image Search Results
Journal: Frontiers in Immunology
Article Title: Adipose-derived stem cell exosomes suppress NLRP3-mediated neuronal pyroptosis to attenuate seizures in a kainic acid-induced temporal lobe epilepsy model
doi: 10.3389/fimmu.2025.1691814
Figure Lengend Snippet: Effects of ADSC-Exos on KA-induced hippocampal neuron damage. (A) Representative Nissl-stained images (200×) showing ADSC-Exos attenuated KA-induced neuron loss in hippocampal CA1 and CA3 regions. (B) Representative TUNEL-stained images (200×) showing ADSC-Exos alleviated KA-induced apoptosis in CA1 and CA3. (C–F) Quantitative analyses of (C) CA1 Nissl+, (D) CA3 Nissl+, (E) CA1 TUNEL+, and (F) CA3 TUNEL+ cells. Individual data points represent values from each mouse (n=5 per group). Data are expressed as mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 (one-way ANOVA with Tukey’s post hoc test).
Article Snippet: The assay was performed according to the manufacturer’s protocol (
Techniques: Staining, TUNEL Assay
Journal: Ecotoxicology and environmental safety
Article Title: Decabromodiphenyl ether (BDE-209) exposure to lactating mice perturbs steroidogenesis and spermatogenesis in adult male offspring.
doi: 10.1016/j.ecoenv.2020.111783
Figure Lengend Snippet: Fig. 6. (A) Western blot analyses of Bax, Bcl-2, PCNA and caspase-3 in testes of adult mice offspring at PND 75 of lactating dams who were exposed to PTU and BDE-209 (500 and 700 mg/kg BW) in comparison to vehicle- treated controls. All protein expression levels were normalized relative to α-tubulin loading control. (B) The densitometric data of Bax, Bcl- 2, PCNA and caspase-3 are presented as the mean of integrated relative density value (IRDV)±S.E.M. of triplicate blots. Representa tive testicular sections showing TUNEL-positive cells (arrows) in seminiferous tubules in adult mice testes of lactating dams who were exposed to PTU (C), vehicle (D) and BDE-209 (E: 500 mg/kg BW; F: 700 mg/kg BW). Scale bar: 50 µm (C-F). (G) Histogram shows an increase in the number of TUNEL-positive cells in testes of PTU and BDE-209-exposed offspring at PND 75. Values are mean ±S.E.M. *Significantly different from controls (p < 0.05) by ANOVA followed by Newman- Keuls’multiple range test.
Article Snippet: TdTmediated
Techniques: Western Blot, Comparison, Expressing, Control, TUNEL Assay